A B C D F G I L M N O P R S T V W Y
addCovariate | Add covariate expression to a function string |
addCovVar | Adding covariate to a given variable in an nlmixr model expression |
addCwres | Add CWRES |
addNpde | NPDE calculation for nlmixr |
addTable | Add table information to nlmixr fit object without tables |
as.dynmodel | Convert fit to classic dynmodel object |
as.focei | Convert fit to FOCEi style fit |
as.focei.nlmixrNlme | Convert fit to FOCEi style fit |
augPred.nlmixrFitData | Augmented Prediction for nlmixr fit |
backwardSearch | Backward covariate search |
Bolus_1CPT | Bolus_1CPT - 1 Compartment Model Simulated Data from ACOP 2016 |
Bolus_1CPTMM | 1 Compartment Model w/ Michaelis-Menten Elimination |
Bolus_2CPT | 2 Compartment Model |
Bolus_2CPTMM | 2 Compartment Model with Michaelis-Menten Clearance |
bootdata | Bootstrap data |
bootplot | Produce trace-plot for fit if applicable |
bootplot.nlmixrFitCore | Produce trace-plot for fit if applicable |
bootstrapFit | Bootstrap nlmixr fit |
boxCox | Cox Box, Yeo Johnson and inverse transformation |
calc.2LL | Log-likelihood using Gaussian Quadrature |
calc.COV | Covariance matrix by Fisher Information Matrix via linearization |
calcCov | Calculate gnlmm variance-covariance matrix of fixed effects |
cholSE | Generalized Cholesky Matrix Decomposition |
configsaem | Configure an SAEM model |
covarSearchAuto | Stepwise Covariate Model-selection (SCM) method |
dynmodel | Fit a non-population dynamic model |
dynmodel.mcmc | Fit a non-population dynamic model using mcmc |
dynmodelControl | Control Options for dynmodel |
focei.eta | Get the FOCEi theta or eta specification for model. |
focei.eta.nlmixrNlme | Get the FOCEi theta or eta specification for model. |
focei.fit | FOCEi fit |
focei.theta | Get the FOCEi theta specification for the model |
focei.theta.nlmixrNlme | Get the FOCEi theta specification for the model |
foceiControl | Control Options for FOCEi |
foceiFit | FOCEi fit |
foceiFit.data.frame | FOCEi fit |
foceiFit.data.frame0 | FOCEi fit |
forwardSearch | Forward covariate search |
frwd_selection | Forward covariate selection for nlme-base non-linear mixed effect models |
gauss.quad | Sets nodes and weights of Gauss-Hermite quadrature |
getOfvType | Set/get Objective function type for a nlmixr object |
getOMEGA | Calculate gnlmm variance-covariance matrix of random effects |
gnlmm | Fit a generalized nonlinear mixed-effect model |
gnlmm2 | Fit a generalized nonlinear mixed-effect model |
gof | Plot of a non-population dynamic model fit |
iBoxCox | Cox Box, Yeo Johnson and inverse transformation |
Infusion_1CPT | Infusion_1CPT - 1 Compartment Model Simulated Data from ACOP 2016 |
ini | nlmixr ini block handling |
initializeCovars | Initializing covariates before estimation |
instant.stan.extension | instant.stan.extension. |
invgaussian | Inverse Guassian absorption model |
iYeoJohnson | Cox Box, Yeo Johnson and inverse transformation |
lin_cmt | concentrations from a linear compartment model |
makeDummies | Create categorical covariates |
makeHockeyStick | Creating Hockey-stick covariates |
metabolite | Parent/Metabolite dataset |
model | nlmixr model block |
nlmeLinCmpt | Fit nlme-based linear compartment mixed-effect model using closed form solution |
nlmeLinCmt | Fit nlme-based linear compartment mixed-effect model using closed form solution |
nlmeOde | Fit nlme-based mixed-effect model using ODE implementation |
nlme_gof | GOF plots for nlme-based mixed-effect models |
nlme_lin_cmpt | Fit nlme-based linear compartment mixed-effect model using closed form solution |
nlme_ode | Fit nlme-based mixed-effect model using ODE implementation |
nlmixr | nlmixr fits population PK and PKPD non-linear mixed effects models. |
nlmixr.function | nlmixr fits population PK and PKPD non-linear mixed effects models. |
nlmixr.nlmixrFitCore | nlmixr fits population PK and PKPD non-linear mixed effects models. |
nlmixr.nlmixrUI | nlmixr fits population PK and PKPD non-linear mixed effects models. |
nlmixrAugPred | Augmented Prediction for nlmixr fit |
nlmixrBounds | Extract the nlmixr bound information from a function. |
nlmixrBounds.eta.names | Get ETA names |
nlmixrBounds.focei.upper.lower | Get upper/lower/names for THETAs |
nlmixrBoundsParser | Functions to assist with setting initial conditions and boundaries |
nlmixrBoundsParser.( | Functions to assist with setting initial conditions and boundaries |
nlmixrDynmodelConvert | Converting nlmixr objects to dynmodel objects |
nlmixrEst | Generic for nlmixr estimation methods |
nlmixrEst.dynmodel | Generic for nlmixr estimation methods |
nlmixrEst.fo | Generic for nlmixr estimation methods |
nlmixrEst.foce | Generic for nlmixr estimation methods |
nlmixrEst.focei | Generic for nlmixr estimation methods |
nlmixrEst.foi | Generic for nlmixr estimation methods |
nlmixrEst.nlme | Generic for nlmixr estimation methods |
nlmixrEst.nlme.free | Generic for nlmixr estimation methods |
nlmixrEst.nlme.mu | Generic for nlmixr estimation methods |
nlmixrEst.nlme.mu.cov | Generic for nlmixr estimation methods |
nlmixrEst.nlmixrEst | Generic for nlmixr estimation methods |
nlmixrEst.posthoc | Generic for nlmixr estimation methods |
nlmixrEst.saem | Generic for nlmixr estimation methods |
nlmixrGill83 | Get the optimal forward difference interval by Gill83 method |
nlmixrHess | Calculate Hessian |
nlmixrLogo | Messages the nlmixr logo... |
nlmixrPred | Predict a nlmixr solved system |
nlmixrSim | Simulate a nlmixr solved system |
nlmixrTest | nlmixTest function for testing |
nlmixrUI.dynmodelfun | Return dynmodel variable translation function |
nlmixrUI.dynmodelfun2 | Return dynmodel variable translation function |
nlmixrUI.focei.fixed | Get parameters that are fixed |
nlmixrUI.focei.inits | Get the FOCEi initializations |
nlmixrUI.nlme.specs | Create the nlme specs list for nlmixr nlme solving |
nlmixrUI.rxode.pred | Return RxODE model with predictions appended |
nlmixrUI.saem.ares | Get initial estimate for ares SAEM. |
nlmixrUI.saem.bres | Get initial estimate for bres SAEM. |
nlmixrUI.saem.cres | Get initial estimate for bres SAEM. |
nlmixrUI.saem.distribution | Get SAEM distribution |
nlmixrUI.saem.eta.trans | Get the eta->eta.trans for SAEM |
nlmixrUI.saem.fit | Generate saem.fit user function. |
nlmixrUI.saem.fixed | Get parameters that are fixed for SAEM |
nlmixrUI.saem.init | Get saem initilization list |
nlmixrUI.saem.init.omega | SAEM's init$omega |
nlmixrUI.saem.init.theta | Generate SAEM initial estimates for THETA. |
nlmixrUI.saem.log.eta | Get model$log.eta for SAEM |
nlmixrUI.saem.model | Generate SAEM model list |
nlmixrUI.saem.model.omega | Get the SAEM model Omega |
nlmixrUI.saem.res.mod | Get the SAEM model$res.mod code |
nlmixrUI.saem.res.name | Get error names for SAEM |
nlmixrUI.saem.rx1 | Return RxODE model with predictions appended |
nlmixrUI.saem.theta.name | Get THETA names for nlmixr's SAEM |
nlmixrUI.theta.pars | Get the Parameter function with THETA/ETAs defined |
nlmixrValidate | Validate nlmixr |
nlmixrVersion | Display nlmixr's version |
nlmixr_fit | Fit a nlmixr model |
nmDocx | Create a run summary word document |
nmLst | Create a large output based on a nlmixr fit |
nmSave | Create a run summary word document |
nmsimplex | Nelder-Mead simplex search |
nmTest | Validate nlmixr |
ofv | Return the objective function |
Oral_1CPT | Oral_1CPT - 1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016 |
performNorm | Perform normalization of the covariate |
pheno_sd | Single Dose Phenobarbitol PK/PD |
plot.dyn.ID | Plot of a non-population dynamic model fit |
plot.dyn.mcmc | Plot of a non-population dynamic model fit using mcmc |
plot.nlmixrFitData | Plot a nlmixr data object |
plot.saemFit | Plot an SAEM model fit |
preCondInv | Calculate the inverse preconditioning matrix |
preconditionFit | Linearly re-parameterize the model to be less sensitive to rounding errors |
predict.nlmixrFitData | Predict a nlmixr solved system |
prediction | Prediction after a gnlmm fit |
print.dyn.ID | Print a non-population dynamic model fit object |
print.dyn.mcmc | Print summary of a non-population dynamic model fit using mcmc |
print.gnlmm.fit | Print a gnlmm fit |
print.nlmixrUI | Print UI function |
print.saemFit | Print an SAEM model fit summary |
pump | Pump failure example dataset |
rats | Pregnant Rat Diet Experiment |
removeCovariate | Remove covariate expression from a function string |
removeCovMultiple | Removing multiple covariates |
removeCovVar | Remove covariate from function string |
residuals.nlmixrFitData | Extract residuals from the FOCEI fit |
rxSolve.nlmixrFitData | Simulate a nlmixr solved system |
saem | Fit an SAEM model |
saem.fit | Fit an SAEM model |
saem.fit.default | Fit an SAEM model |
saem.fit.function | Fit an SAEM model |
saem.fit.nlmixr.ui.nlme | Fit an SAEM model |
saem.fit.nlmixrUI | Fit an SAEM model |
saem.fit.RxODE | Fit an SAEM model |
saemControl | Control Options for SAEM |
setCov | Set the covariance type based on prior calculated covariances |
setOfv | Set/get Objective function type for a nlmixr object |
simulate.nlmixrFitData | Simulate a nlmixr solved system |
solve.nlmixrFitData | Simulate a nlmixr solved system |
sqrtm | Return the square root of general square matrix A |
summary.dyn.ID | Summary of a non-population dynamic model fit |
summary.dyn.mcmc | Print summary of a non-population dynamic model fit using mcmc |
summary.saemFit | Print an SAEM model fit summary |
tableControl | Output table/data.frame options |
theo_md | Multiple dose theophylline PK data |
theo_sd | Multiple dose theophylline PK data |
traceplot | Produce trace-plot for fit if applicable |
traceplot.nlmixrFitCore | Produce trace-plot for fit if applicable |
VarCorr.nlmixrNlme | Return VarCorr for nlmixr nlme |
vpc | Vpc function for nlmixr |
vpc.default | Vpc function for nlmixr |
vpc.nlmixrFitData | VPC based on ui model |
vpc.nlmixrNlme | Visual predictive check (VPC) for nlmixr nlme objects |
vpc.nlmixrVpc | VPC based on ui model |
vpc.saemFit | VPC for nlmixr saemFit objects |
vpc.ui | VPC based on ui model |
vpcNlmixrNlme | Visual predictive check (VPC) for nlmixr nlme objects |
vpc_nlmixr_nlme | Visual predictive check (VPC) for nlmixr nlme objects |
vpc_saemFit | VPC for nlmixr saemFit objects |
vpc_ui | VPC based on ui model |
Wang2007 | Simulated Data Set for comparing objective functions |
warfarin | Warfarin PK/PD data |
yeoJohnson | Cox Box, Yeo Johnson and inverse transformation |