NORMAgene: Data-Driven qRT-PCR Normalization Using NORMAgene

Enables correction for technical variance in raw quantitative reverse transcription polymerase chain reaction (qRT-PCR) data using the least squares-based NORMAgene data-driven normalization algorithm originally described by Heckmann et al. (2011) <doi:10.1186/1471-2105-12-250>. Performs normalization of raw crossing threshold values (CT) and also calculates relative variability metrics that can be used to assess the impact of normalization on variance.

Version: 0.1.1
Depends: R (≥ 3.5)
Suggests: testthat (≥ 3.0.0)
Published: 2026-02-28
DOI: 10.32614/CRAN.package.NORMAgene (may not be active yet)
Author: Grant C. O'Connell ORCID iD [aut, cre]
Maintainer: Grant C. O'Connell <goconnell.phd at gmail.com>
License: GPL-3
NeedsCompilation: no
Citation: NORMAgene citation info
CRAN checks: NORMAgene results

Documentation:

Reference manual: NORMAgene.html , NORMAgene.pdf

Downloads:

Package source: NORMAgene_0.1.1.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): NORMAgene_0.1.1.tgz, r-oldrel (arm64): NORMAgene_0.1.1.tgz, r-release (x86_64): not available, r-oldrel (x86_64): NORMAgene_0.1.1.tgz

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