survHC: Higher Criticism Tests for Non-Proportional Hazard Deviations
Implements omnibus tests for comparing two right-censored survival
samples that are powerful against sparse departures from equal hazards,
where the hazard difference is concentrated in a small and a priori unknown
subset of the follow-up. Exact hypergeometric p-values are computed for each
time interval and aggregated with the Higher Criticism statistic of Donoho
and Jin (2004) <doi:10.1214/009053604000000265>, or alternatively with the
Berk-Jones, Fisher or minimum-p statistics. Global p-values are obtained by
permuting group labels, and the intervals driving a detection can be
recovered for diagnostic plotting. Tests accept either two samples as
vectors or the usual survival formula. The method is described in Kipnis,
Galili and Yakhini (2026) <doi:10.1093/biomet/asaf075>, and the companion
application note is Kipnis, Galili and Yakhini (2026)
<doi:10.48550/arXiv.2610.07268>.
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